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In contrast, acid output measurement may be a superior method to documenting effective PPI therapy because it takes into account the complete gastric aspirate rather than depend on an isolated intragastric measurement.
Pantoprazole 20 mg is an effective maintenance therapy for patients with gastro-oesophageal reflux disease.
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Prevalence is higher in third world countries where it is estimated at about 70% of the population, whereas developed countries show a maximum of 40% ratio.
Controloc is an international brand name for the drug pantoprazole, a proton-pump inhibitor that is used for the treatment and maintenance of gastroesophageal reflux disease (GERD) and hypersecretory gastric disorders including Zollinger-Ellison syndrome.
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Short-term (up to 8 wk) treatment in the healing and symptomatic relief of erosive esophagitis associated with gastroesophageal reflux disease (GERD); long-term treatment of pathological hypersecretory conditions, including Zollinger-Ellison syndrome; maintenance of healing of erosive esophagitis associated with GERD.
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Protonix (pantoprazole) for GERD: "I had heartburn and a history of an ulcer so my doctor put me on Protonix and when taking it daily I feel great, however with the new information about this kind of drug being linked to dementia and also that is can cause one to be addicted to it and cause rebound acid I decided to stop it.
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Administration of pantoprazole sodium delayed-release tablets with food may delay its absorption up to 2 hours or longer; however, the C max and the extent of pantoprazole absorption (AUC) are not altered.
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In 39 patients treated with oral Pantoprazole 40 mg to 240 mg daily (majority receiving 40 mg to 80 mg) for up to 5 years, there was a moderate increase in ECL-cell density, starting after the first year of use, which appeared to plateau after 4 years.
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