金沙娱城官网

湖南省百人计划青年人才----李军华(2020)

时间: 2020/03/04   作者:   点击:

 

基本信息:

李军华,男, 1982年8月生,江西新余人,博士,副教授,邮箱:lijunhua@hunau.edu.cn,地址:金沙娱城官网app求索楼204,研究方向:鱼类免疫与病害防控

教育及科研经历:

2000年09月—2004年07月,南昌大学,学士

2004年09月—2007年07月,南昌大学,硕士,导师:文春根

2007年09月—2011年07月,中国科学院水生生物研究所,博士,导师:聂品

2011年09月—2013年12月,中国科学院水生生物研究所,助理研究员

2014年03月—2019年04月,美国南加州大学,博士后,合作导师:冯平辉

2019年05月—2020年01月,华中农业大学,助理研究员

2020年03月—现在,金沙娱城官网app,副教授

 

研究领域:

主要研究方向包括:(1)水产养殖暴发温度依赖的病毒性及细菌性传染病分子机理与免疫防治;(2)鱼类先天免疫分子水生环境演化适应的分子机制

 

发表论文:

1.     Li JH, Zhao J, Xu SM, Zhang S, Zhang JJ, Xiao J, Gao RY, Tian M, Zeng Y, Lee K, Tarakanova V, Lan K, Feng H, Feng PH*. (2019) Antiviral activity of a purine synthesis enzyme reveals a key role of deamidation in regulating protein nuclear import. Science Advances. 5, eaaw7373.

2.     Zhang JJ, Zhao J, Xu SM, Li JH, He SP, Zeng Y, Xie LS, Xie N, Liu T, Seo GJ, Chen L, Stabell A, Xia ZX, Sawyer S, Jung J, Huang CH, Feng PH*. (2018) Species-specific deamidation of cGAS facilitates herpes simplex virus lytic replication. Cell Host Microbe. 24, 234–248.

3.     Ding CM, He J, Zhao J, Li JH, Chen J, Liao WY, Zeng Y, Zhong J, Wei CY, Zhang LM, Zhou M, Jia ZM, Zhang YT, Li H, Zhou YZ, Xiao XL, Han D, Li C, Zhu Z, Xia ZX, Peng J*. (2018) β-catenin regulates innate immunity response in colorectal cancer cells. Cell Proliferation, doi: 10.1111/cpr.12464.

4.     Ding CM, He J, Liao W, Chen J, Li JH, He GS, Jia ZM, Zhang YT, Luo JX, Dai XM, Zhang LM, Li H, Zhou YZ, Lu A, Xia ZX, Zhao J, Peng J*. (2017) Regulation of WNT/β-catenin signaling by carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD) in colorectal cancer cell. International Journal of Clinical and Experimental Medicine, 10, 16243-16253.

5.     Zhao J, Li JH, Xu SM, Feng PH*. (2016) Emerging Roles of Protein Deamidation in Innate Immune Signaling. Journal of Virology. 90, 4262-4268.

6.     Zou PF, Chang MX, Li Y, Xue NN, Li JH, Chen XN, Nie P*. (2016) NOD2 in zebrafish functions in antibacterial and also antiviral responses via NF-κB, and also MDA5, RIG-I and MAVS. Fish and Shellfish Immunology, 55, 173-185.

7.     Zhao J, He SP, Minassian A, Li JH, Feng PH*. (2015) Recent advances on viral manipulation of NF-κB signaling pathway. Current Opinion in Virology, 15, 103-111.

8.     Li JH, Yu ZL, Xue NN, Zou PF, Hu JY, Nie P, Chang MX*. (2014) Molecular cloning and functional characterization of peptidoglycan recognition protein 6 in grass carp Ctenopharyngodon idella. Developmental and Comparative Immunology. 42, 244-55.

9.     Yu ZL, Li JH, Xue NN, Hu JY, Nie P, Chang MX*. (2014) Expression and functional characterization of PGRP6 splice variants in grass carp Ctenopharyngodon idella. Developmental and Comparative Immunology, 47, 264-74.

10.  Zou PF, Chang MX, Xue NN, Liu XQ, Li JH, Fu JP, Chen SN, Nie P*. (2014) MDA5 in zebrafish provoking higher IFN-promoter activity through signaling enhancing of its shorter splicing variant. Immunology, 141, 192-202.

11.  Li JH, Chang MX*, Xue NN, Nie P*. (2013) Functional characterization of a short peptidoglycan recognition protein, PGRP5 in grass carp Ctenopharyngodon idella. Fish and Shellfish Immunology. 35, 221-230.

12.  Yang ZY, Li JH, Li Y, Wu HJ*. (2013) Molecular cloning and functional characterization of a short peptidoglycan recognition protein (HcPGRPS1) from Hyriopsis cumingi. Molecular Immunology, 56, 729-738.

13.   Wang GL, Li JH, Zou PF, Xie HX, Huang B, Nie P, Chang MX*. (2012) Expression pattern, promoter activity and bactericidal property of β–defensin from the mandarin fish Siniperca chuatsi. Fish and Shellfish Immunology, 33, 522-531.

 

奖励与荣誉:

2020年湖南省“百人计划”青年项目

2016年第19届KSHV国际会议作主题报告获Travel Award

 

项目来源:

金沙娱城官网app人才引进启动经费,50万元,主持

 

团队建设:

课题组拟招聘2-4名科研助理,欢迎热爱科研、有志于水产病害防控的本科生、研究生加入

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